Long-term use of Benadryl, an over-the-counter allergy medication, has been linked to an increased dementia risk. In lieu of Benadryl, possible alternatives include cetirizine (Zyrtec), fexofenadine (Allegra) and loratadine (Claritin).
Does loratadine cause memory loss?
In the brain, they inhibit activity in the memory and learning centers, which can lead to memory loss. Alternatives: Newer-generation antihistamines such as loratadine (Claritin) and cetirizine (Zyrtec) are better tolerated by older patients and do not present the same risks to memory and cognition.
Are antihistamines linked to dementia?
In a report published in JAMA Internal Medicine, researchers offers compelling evidence of a link between long-term use of anticholinergic medications like Benadryl and dementia. Anticholinergic drugs block the action of acetylcholine. This substance transmits messages in the nervous system.
Does loratadine have anticholinergic effects?
One of these studies9 gave loratadine 2 points on the Anticholinergic Risk Scale, indicating that it entails intermediate risk; another study8 gave loratadine 0 points, which means that it has no known anticholinergic properties.
Can you take loratadine long term?
Loratadine is unlikely to do you any harm if you take it for a long time. However, it’s best to take loratadine only for as long as you need to.
What are the side effect of loratadine?
Loratadine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache.
- dry mouth.
- nosebleed.
- sore throat.
- mouth sores.
- difficulty falling asleep or staying asleep.
- nervousness.
- weakness.
What is the number one food that fights dementia?
Researchers developed the diet by looking at the Mediterranean and DASH diets, then focusing on the foods with the most compelling findings in dementia prevention. Vegetables, especially leafy greens, rose to the top. In general, fruit didn’t, though berries made the list.
What are the side effects of long term use of antihistamines?
These common side effects include sedation, impaired motor function, dizziness, dry mouth and throat, blurred vision, urinary retention and constipation. Antihistamines can worsen urinary retention and narrow angle glaucoma. The antihistamines rarely cause liver injury.
Is it OK to take antihistamines long term?
“The most common side effects you tend to see are fatigue, headaches, and dry mouth,” says Shih. If you’re someone for whom the benefits of regular antihistamine use far outweighs the occasional minor side effect, longterm use is safe for most adults and children, he adds.17 мая 2018 г.
Can antihistamines cause memory loss?
Medications. A number of prescription and over-the-counter medications can interfere with or cause loss of memory. Possible culprits include: antidepressants, antihistamines, anti-anxiety medications, muscle relaxants, tranquilizers, sleeping pills, and pain medications given after surgery.
Is loratadine safe for seniors?
Loratadine, cetrizine, and fexofenadine all have excellent safety records. Their cardiovascular safety has been demonstrated in drug-interaction studies, elevated-dose studies, and clinical trials. These three antihistamines have also been shown safe in special populations, including pediatric and elderly patients.
What medications are linked to dementia?
Anticholinergics from the following groups increased dementia risk when used at the highest doses:
- antidepressants OR 1.29 (95% CI 1.24 to 1.34)
- anti-Parkinson’s drugs OR 1.52 (95% CI 1.16 to 2.00)
- antipsychotics OR 1.70 (95% CI 1.53 to 1.90)
- anti-epileptics OR 1.39 (95% CI 1.22 to 1.57)
What are the anticholinergic side effects of antihistamines?
Antihistamine Risks and Anticholinergic Syndrome
These antihistamines also are potent muscarinic receptor antagonists that can lead to serious anticholinergic side effects, such as sinus tachycardia, dry skin, dry mucous membranes, dilated pupils, constipation, ileus, urinary retention, and agitated delirium.
Can I just stop taking loratadine?
Getting the most from your treatment. Most people only need to take an antihistamine for a short while when they have symptoms. You should stop taking loratadine once your symptoms have eased. Although loratadine is classed as a non-drowsy antihistamine, it can still cause drowsiness in a few people.
Is loratadine safe to take every day?
Loratadine is usually taken once a day. During the pollen season, your doctor may advise you to take it every day if you suffer from seasonal allergic rhinitis. Although loratadine is unlikely to make you drowsy, some people are susceptible to this effect.
Can I take loratadine 10 mg twice a day?
No, the maximum recommended daily dose of loratadine is 10mg once daily.