Using diphenhydrAMINE together with sertraline may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.
Does Benadryl interact with any medications?
Benadryl Allergy (diphenhydramine) Drug Interactions
A total of 404 drugs are known to interact with Benadryl Allergy (diphenhydramine). Show all medications in the database that may interact with Benadryl Allergy (diphenhydramine).
Can you take allergy medicine with antidepressants?
Usually it is better to avoid taking antihistamines at the same time as certain medicines, including: Certain types of antidepressants. Tricyclic antidepressants such as amitriptyline and lofepramine may interact with antihistamines. Other antidepressants such as moclobemide.
What should you not take with Benadryl?
Examples of medications that may interact with Benadryl include:
- stomach ulcer medicine.
- cough and cold medicine.
- other antihistamines.
- diazepam (Valium)
When should you not take Benadryl?
Call your doctor if the condition you are treating with diphenhydramine does not improve, or if you have a fever with a headache, cough, or skin rash. Do not use diphenhydramine for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms.
Can Benadryl help with anxiety?
One of the biggest advantages of using an OTC medication such as Benadryl to treat anxiety is that it is fast-acting and convenient. This can be helpful if you need to reduce symptoms of mild anxiety quickly. Because Benadryl causes many people to feel drowsy, it can also help aid in sleep.
What are the negative effects of Benadryl?
Common side effects may include:
- dizziness, drowsiness, loss of coordination;
- dry mouth, nose, or throat;
- constipation, upset stomach;
- dry eyes, blurred vision; or.
- day-time drowsiness or “hangover” feeling after night-time use.
What medications should not be taken with SSRI?
Some of the medications that can interact with some SSRIs include:
- non-steroidal anti-inflammatory drugs (NSAIDs) – a common type of painkiller that includes ibuprofen, diclofenac or naproxen.
- antiplatelets – a type of medication used to prevent blood clots, such as low-dose aspirin and clopidogrel.
What drugs should not be taken with sertraline?
What Other Medications May Interact With Sertraline? Sertraline should not be taken with or within two weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), rasagiline (Azilect®), and selegiline (Emsam®).
Does Benadryl affect serotonin?
Diphenhydramine, a first-generation antihistamine that acts as an inverse agonist on the H1 receptor  may also inhibit the reuptake of serotonin. It is known that SSRIs like Fluoxetine are analogs of diphenhydramine . Although weaker, diphenhydramine does retain some activity at the serotonin receptor.
Can you drink wine with Benadryl?
Talk with your doctor
Benadryl is a strong drug. Using it safely means not drinking alcohol while you take it. Combining the drug with alcohol can cause dangerous effects, such as extreme drowsiness and impaired motor skills and alertness.
What does Benadryl do to your body?
This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its drying effects on such symptoms as watery eyes and runny nose are caused by blocking another natural substance made by your body (acetylcholine).
Does Benadryl reduce inflammation?
A quick-acting allergy medication, such as diphenhydramine (Benadryl), can help reduce swelling and itching after an insect bite or sting. Drug allergies can also cause swollen lips.
Does Benadryl raise BP?
Benadryl may cause a drop in blood pressure which may cause symptoms such as dizziness and increase your risk of falls. Remove any fall hazards in your home (such as rugs) and talk to your doctor if you are experiencing severe dizziness every time you stand up.
Is it OK to take 50 mg of Benadryl?
For adults and teens, the diphenhydramine dosage is 25 to 50 mg every 4 to 6 hours. The maximum amount you should take in one day is 300 mg. Keep in mind, taking higher doses can increase the risk of side effects, including drowsiness.
Is taking Benadryl every night bad for you?
Taking Benadryl to help you get to sleep is okay in small doses once in a while ― but, again, it doesn’t lead to better quality sleep, Elliott said. Because antihistamines can peer pressure your body to spend more time in the lighter stages of sleep, the eight hours you clock in bed might end up feeling more like five.